Organic disulfides
Medchemexpress LLC NX-2127 | 2416131-46-7 | C39H45N9O5 | 500 MG
Zelebrudomide (NX-2127) is an orally active PROTAC degrader that targets Bruton's Tyrosine Kinase (Btk). It inhibits the proliferation of BTKC481S mutant TMD8 cells more effectively than Ibrutinib. In vivo, it demonstrates potent degradation of BTK in cynomolgus monkeys and leads to superior tumor growth inhibition in both WT TMD8 and C481S mutant xenograft models in mice.
- Inhibits proliferation of BTKC481S mutant TMD8 cells
- Catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3)
- Stimulates T cell activation and increases IL-2 production
- Demonstrates potent degradation of BTK in cynomolgus monkeys
- Leads to superior tumor growth inhibition in xenograft models in mice
Medchemexpress LLC Zelebrudomide (NX-2127) | 2416131-46-7 | C39H45N9O5 | 50 MG
Zelebrudomide (NX-2127) is an orally active PROTAC degrader that targets Bruton's Tyrosine Kinase (Btk). It inhibits the proliferation of BTKC481S mutant TMD8 cells more effectively than Ibrutinib and appears as a light yellow to yellow solid. The compound has a molecular weight of 719.83.
- Targets Bruton's Tyrosine Kinase (Btk)
- Inhibits the proliferation of BTKC481S mutant TMD8 cells
- Catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3)
- Stimulates T cell activation
- Increases IL-2 production in primary human T cells
- Demonstrates potent degradation of BTK in cynomolgus monkeys in vivo
- Leads to superior tumor growth inhibition in both WT TMD8 and C481S mutant xenograft models in mice
Medchemexpress LLC NX-2127 | 2416131-46-7 | C39H45N9O5 | 1 G
NX-2127 | 2416131-46-7 | C39H45N9O5 | 1 G
Medchemexpress LLC Diphenyl disulfide | 882-33-7 | MFCD00003065 | 100.0% | 218.35 g/mol | C12H10S2 | 1g
Diphenyl disulfide is an endogenous metabolite Diphenyl disulfide is a pharmaceutical intermediate Diphenyl disulfide can be coupled with aryl iodide to synthesize asymmetric aryl sulfide[1][2]
eMolecules Ambeed / 2-(4-Nitrobenzamido)acetic acid / 1g / 586036432 / A703345 / / 2645-07-0 / MFCD00007349 / 224.172 / C9H8N2O5
Ambeed / 2-(4-Nitrobenzamido)acetic acid / 1g / 586036432 / A703345 / / 2645-07-0 / MFCD00007349 / 224.172 / C9H8N2O5
Selleck Chemical LLC NX-2127-E1381-5MG
NX-2127 is a unique potent inhibitor of BTK that prevents its functions by catalyzing the ubiquitylation and proteasomal degradation of BTK rather than via direct binding NX-2127 stimulates T cell activation and increases IL-2 production in primary human T Cells
Medchemexpress LLC Hydroxyethyl disulfide | 1892-29-1 | MFCD00002906 | 98.8% | 154.25 g/mol | C4H10O2S2 | 10 G
Hydroxyethyl disulfide is a small-molecule laboratory reagent used in biochemical research. It is reported to interact with thymidylate synthase pathways and is provided with supporting documentation such as a certificate of analysis and safety data sheet. The compound is commonly used as a reagent or intermediate in chemical and biochemical studies.
- Purity 98.8% (reported)
- Cas number 1892-29-1
- Molecular formula C4H10O2S2
- Molecular weight 154.25 g/mol
- Available as a 10 G package
Medchemexpress LLC HY-W009390 5g Medchemexpress, DL-Homocystine CAS:870-93-9 Purity:>98%
Medchemexpress, HY-W009390 5g DL-Homocystine CAS:870-93-9 DL-Homocystine is the double-bonded form of homocysteine and homocysteine is recognized as an important substance in the pathogenesis and pathophysiology of schizophrenia. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC N N-Dicyclohexyl-2-b 100g
N N-Dicyclohexyl-2-benzothiazolesulfenamide is a compound with reproductive and developmental toxicity that can affect body weight gain reproductive organ weight and multiple reproductive and developmental indicators in rats
eMolecules Medchem Express / DL-Homocystine-33334444-d8 / 5mg / 771359132 / HY-W009390S / / 108641-82-3 / MFCD00209738 / 276.390 / C8H16N2O4S2
Medchem Express / DL-Homocystine-33334444-d8 / 5mg / 771359132 / HY-W009390S / / 108641-82-3 / MFCD00209738 / 276.390 / C8H16N2O4S2
Sigma Aldrich Fine Chemicals Biosciences Propyl disulfide 97 FG5KG
Propyl disulfide is a volatile flavor compound mainly found in allium species such as onion chive and scallions.
Medchemexpress LLC Dipropyl disulfide | 629-19-6 | MFCD00009378 | 99.3% | 150.31 g/mol | C6H14S2 | 1 G
Dipropyl disulfide is an organosulfur compound supplied as a high-purity research standard for biochemical and metabolic studies, analytical reference work, and assay development. It is offered in liquid and ready-to-use solution formats for convenient laboratory handling.
- High purity (99.3%).
- Molecular formula C6H14S2; molecular weight 150.31 g/mol.
- Available as 1 G liquid and larger pack sizes; also as 10 mM 1 mL in DMSO solutions.
- Storage: pure form -20°C (up to 3 years); in solvent -80°C (6 months).
- Suitable for metabolic studies and analytical reference use.
Medchemexpress LLC Captopril disulfide | 64806-05-9 | MFCD08063643 | 99.3% | 432.55 | C18H28N2O6S2 | 5MG
Captopril disulfide is the symmetrical disulfide metabolite of the ACE inhibitor captopril, provided as a research-grade analytical standard for studies of angiotensin-converting enzyme inhibition and antihypertensive drug metabolism. Molecular formula C18H28N2O6S2, molecular weight 432.55, CAS 64806-05-9.
- High reported purity (99.29%).
- Analytical standard for metabolite and pharmacokinetic studies.
- Applicable to ACE activity and antihypertensive research.
- Available in milligram-scale pack sizes suitable for small-scale experiments.
- Stable white solid with defined molecular identity.